Search results for "Angiogenesis Modulating Agents"

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From the oxygen to the organ protection: Erythropoietin as protagonist in internal medicine

2006

Erythropoietin (EPO), already known as the stimulating hormone for erythropoiesis, has shown different and interesting pleiotropic actions. It does not only affect erythroid cells, but also myeloid cells, lymphocytes and megakaryocytes. This hormone can also enhance phagocytic function of the polymorphonuclear cells and reduce the activation of macrophages, thus modulating the inflammatory process.Moreover, hematopoietic and endothelial cells probably have the same cellular origin, and the discovery of erythropoietin receptors (EPO-R) also on mesangial and myocardial cells, smooth muscle fibrocells and neurons has prompted the study of the non-erythropoietic functions of this hormone.The in…

Vascular Endothelial Growth Factor Amedicine.medical_specialtyIschemiaNeovascularizationIschemiahemic and lymphatic diseasesInternal medicinemedicineErythropoietin (EPO); pleiotropic actions; erythropoietin receptors (EPO-R); VEGFHumansOxygen tensionReceptorHypoxiaErythropoietinPharmacologyClinical Trials as Topicbusiness.industryPleiotropic actionerythropoietin receptors (EPO-R)pleiotropic actionsAngiogenesis Modulating AgentsApoptosiAnemiaShockHematologymedicine.diseaseVEGFHaematopoiesisAngiogenesiEndocrinologyApoptosisErythropoietinErythropoietin (EPO)Erythropoiesismedicine.symptombusinessCardiology and Cardiovascular MedicineHormonemedicine.drugReceptor
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